Difference between revisions of "CS382:Unit-phylogeny"
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== Basis == | == Basis == | ||
phylogenetic trees are structures which show the homology between similar proteins, in different organisms. They | phylogenetic trees are structures which show the homology between similar proteins, in different organisms. They | ||
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Cladistics (constructing a phylogenetic tree). Start with a common protein or gene amongst a group of organisms and construct a model for how they diverged evolutionarily based on evidence from that gene. This could also start simpler with looking at homologies and analogies and constructing a tree based on that (old way), then moving to the more cutting research with the genes. Would give an opportunity to talk about the computing power behind searching large databases of proteins or nucleotides. | Cladistics (constructing a phylogenetic tree). Start with a common protein or gene amongst a group of organisms and construct a model for how they diverged evolutionarily based on evidence from that gene. This could also start simpler with looking at homologies and analogies and constructing a tree based on that (old way), then moving to the more cutting research with the genes. Would give an opportunity to talk about the computing power behind searching large databases of proteins or nucleotides. | ||
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| + | == Comments == | ||
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| + | == To Do == | ||
| + | * Currently looking at Biology Workbench or other software for construction. | ||
Revision as of 10:37, 28 January 2009
Basis
phylogenetic trees are structures which show the homology between similar proteins, in different organisms. They
Assembling a phylogenetic tree - Look at models available from the bioinformatics toolbench and experiment with different ways comparing protein similarity. This could be tied into a lecture on protein folding as protein homology like indicative of phylogeny.
Cladistics (constructing a phylogenetic tree). Start with a common protein or gene amongst a group of organisms and construct a model for how they diverged evolutionarily based on evidence from that gene. This could also start simpler with looking at homologies and analogies and constructing a tree based on that (old way), then moving to the more cutting research with the genes. Would give an opportunity to talk about the computing power behind searching large databases of proteins or nucleotides.
Comments
Pros
Cons
Comments
To Do
- Currently looking at Biology Workbench or other software for construction.
